Microarray Data integration and Top-Down Modeling of Gene Regulation

Filkov, Vladimir (2003) Microarray Data integration and Top-Down Modeling of Gene Regulation. In: Proceedings of the Fourth Conference on Informatics and Information Technology. Institute of Informatics, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University in Skopje, Macedonia, Skopje, Macedonia, pp. 423-432. ISBN 9989-668-45-0


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Microarray technologies allow monitoring of gene activity (or expression) of thousands of genes in parallel at the same time. Although very powerful, their complexity makes the observed data very difficult to integrate across experiments. In the first part of this paper I will introduce the microarray technology and several of our bioinformatics approaches for integrating multiple gene expression data sets using combinatorial and visualization methods. In the second part of the paper I will present some thoughts towards formalizing biological models of gene regulation towards a language of transcription.

Item Type: Book Section
Uncontrolled Keywords: data integration, consensus clustering, microarrays, modeling gene regulation
Subjects: International Conference on Informatics and Information Technologies > Theoretical backgrounds of CS
Depositing User: Vangel Ajanovski
Date Deposited: 28 Oct 2016 00:15
Last Modified: 28 Oct 2016 00:15
URI: http://eprints.finki.ukim.mk/id/eprint/11335

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